Function of PrPC(1-OPRD) in biological activities of gastric cancer cell lines

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چکیده

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Function of PrPC (1-OPRD) in biological activities of gastric cancer cell lines

Approximately 10-15% of the human prion disease is inherited and one of the important genetic mutations occurs in the octapeptide repeat region of prion protein gene. One of the variants, one octapeptide repeat deletion (1-OPRD), existed in several gastric cancer cell lines and its mutation frequency was higher in gastric cancer cases. However, the biological functions of it remain unknown. Wil...

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ژورنال

عنوان ژورنال: Journal of Cellular and Molecular Medicine

سال: 2009

ISSN: 1582-1838,1582-4934

DOI: 10.1111/j.1582-4934.2009.00687.x